Pre_GI: BLASTP Hits

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Query: NC_004557:2677155:2693199 Clostridium tetani E88, complete genome

Start: 2693199, End: 2693960, Length: 762

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013216:4097056:411783341178334118570738Desulfotomaculum acetoxidans DSM 771, complete genomePHP domain protein2e-29129
NC_014633:339181:348500348500349249750Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequencePHP domain-containing protein5e-21101
NC_003551:154883:165843165843166553711Methanopyrus kandleri AV19, complete genomePredicted phosphatase of the PHP family2e-1996.3
NC_016816:2782373:279550227955022796239738Pantoea ananatis LMG 5342, complete genomePHP domain-containing protein2e-1995.9
NC_015968:1709680:171420017142001714937738Enterobacter asburiae LF7a chromosome, complete genomehydrolase ycdX9e-1994
NC_016514:1701273:170400717040071704744738Enterobacter cloacae EcWSU1 chromosome, complete genomeprotein YcdX3e-1892
NC_009092:1599526:163408416340841634827744Shewanella loihica PV-4, complete genomePHP C-terminal domain protein5e-1891.7
NC_013716:1178383:119628011962801197017738Citrobacter rodentium ICC168, complete genomeputative phosphoesterase4e-1788.6
NC_003198:1117687:113636411363641137101738Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein4e-1685.1
NC_010102:1979742:198177519817751982512738Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein4e-1685.1
NC_006511:1770000:177205117720511772788738Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein4e-1685.1
NC_011080:1209935:122787512278751228612738Salmonella enterica subsp. enterica serovar Newport str. SL254,putative hydrolase4e-1685.1
NC_004631:1842050:184408218440821844819738Salmonella enterica subsp. enterica serovar Typhi Ty2, completehypothetical protein4e-1685.1
NC_006905:1186895:120617412061741206911738Salmonella enterica subsp. enterica serovar Choleraesuis strhypothetical protein4e-1685.1
NC_011149:1987291:198729119872911988028738Salmonella enterica subsp. enterica serovar Agona str. SL483,putative hydrolase4e-1685.1
NC_003197:1207597:122608812260881226825738Salmonella typhimurium LT2, complete genomehypothetical protein4e-1685.1
NC_011083:1216500:123043712304371231174738Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,putative hydrolase4e-1685.1
NC_011147:1763681:176723417672341767971738Salmonella enterica subsp. enterica serovar Paratyphi A strhydrolase4e-1685.1
NC_011205:2137696:214017221401722140909738Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853hydrolase4e-1685.1
NC_017046:1164176:118230111823011183038738Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein4e-1685.1
NC_016863:1165232:118354111835411184278738Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative hydrolase4e-1685.1
NC_016860:1205282:122377412237741224511738Salmonella enterica subsp. enterica serovar Typhimurium strputative hydrolase4e-1685.1
NC_016857:1163919:118222811822281182965738Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative hydrolase4e-1685.1
NC_016856:1165941:118425011842501184987738Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative hydrolase4e-1685.1
NC_016832:1838220:184111718411171841854738Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hydrolase4e-1685.1
NC_016810:1163919:118222811822281182965738Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein4e-1685.1
NC_012125:2646792:264882426488242649561738Salmonella enterica subsp. enterica serovar Paratyphi C strainhydrolase4e-1685.1
NC_011294:2009388:201186420118642012601738Salmonella enterica subsp. enterica serovar Enteritidis strhydrolase4e-1685.1
NC_011094:1166271:118439511843951185132738Salmonella enterica subsp. enterica serovar Schwarzengrund strhydrolase6e-1684.7
NC_014121:2629075:264547226454722646209738Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completePHP family protein6e-1684.7
NC_017265:2213500:223273522327352233472738Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative zinc-binding hydrolase1e-1584
NC_017168:3433804:345336734533673454104738Yersinia pestis A1122 chromosome, complete genomeputative hydrolase1e-1584
NC_014029:2285323:230505923050592305796738Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-1584
NC_009708:2347350:236583623658362366573738Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehydrolase1e-1584
NC_009381:1205900:122558412255841226321738Yersinia pestis Pestoides F chromosome, complete genomeputative hydrolase1e-1584
NC_010465:2383219:240294024029402403677738Yersinia pseudotuberculosis YPIII, complete genomePHP domain protein1e-1584
NC_015663:3466471:350030035003003501040741Enterobacter aerogenes KCTC 2190 chromosome, complete genomeputative hydrolase1e-1584
NC_010159:2546590:256620325662032566940738Yersinia pestis Angola, complete genomeputative phosphoesterase1e-1583.6
NC_004088:2491303:251107125110712511919849Yersinia pestis KIM, complete genomehypothetical protein2e-1582.8
NC_015958:2527376:2548421254842125501391719Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomePHP domain-containing protein3e-1582
NC_013894:1476956:1477920147792014796441725Thermocrinis albus DSM 14484 chromosome, complete genomeDNA-directed DNA polymerase4e-1478.6
NC_017160:2212806:223280222328022233296495Yersinia pestis D182038 chromosome, complete genomehypothetical protein5e-1478.2
AC_000091:1083798:109912010991201099857738Escherichia coli W3110 DNA, complete genomepredicted zinc-binding hydrolase1e-1377
NC_000913:1087062:109810210981021098839738Escherichia coli K12, complete genomehypothetical protein1e-1377
NC_004337:1065609:107376010737601074497738Shigella flexneri 2a str. 301, complete genomehypothetical protein2e-1376.3
NC_008258:1076922:109314010931401093877738Shigella flexneri 5 str. 8401, complete genomehypothetical protein2e-1376.3
NC_010468:2809125:281029628102962811033738Escherichia coli ATCC 8739, complete genomePHP domain protein2e-1375.9
NC_013517:3997448:401771140177114018442732Sebaldella termitidis ATCC 33386, complete genomePHP domain protein3e-1375.9
NC_010320:671699:6757916757916775031713Thermoanaerobacter sp. X514 chromosome, complete genomephosphotransferase domain-containing protein4e-1375.1
NC_010067:1782998:178501217850121785749738Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein6e-1374.7
NC_010321:244371:2443712443712461011731Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completephosphotransferase domain-containing protein1e-1273.9
NC_014391:6640327:6652903665290366539731071Micromonospora aurantiaca ATCC 27029 chromosome, complete genomePHP domain-containing protein2e-1273.2
NC_016894:2931213:295346229534622954217756Acetobacterium woodii DSM 1030 chromosome, complete genomeputative hydrolase3e-1272
NC_014323:2680085:2714539271453927163201782Herbaspirillum seropedicae SmR1 chromosome, complete genomeDNA polymerase IV protein2e-1066.2
NC_009662:1285826:1304084130408413057991716Nitratiruptor sp. SB155-2, complete genomefamily X DNA polymerase IV4e-1065.1
NC_015635:3542125:3566937356693735679531017Microlunatus phosphovorus NM-1, complete genomehypothetical protein5e-1065.1
NC_004461:813748:8290838290838307921710Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein5e-1065.1
NC_002976:707827:7231507231507248591710Staphylococcus epidermidis RP62A, complete genomehypothetical protein7e-1064.3
NC_015942:2293455:229528622952862296152867Acidithiobacillus ferrivorans SS3 chromosome, complete genomehistidinol phosphate phosphatase HisJ family1e-0963.5
NC_004722:4496000:4499294449929445010151722Bacillus cereus ATCC 14579, complete genomehypothetical protein4e-0962
NC_020389:1936000:1945492194549219472461755Methanosarcina mazei Tuc01, complete genomeDNA polymerase X family4e-0962
NC_003909:4333097:4335477433547743371951719Bacillus cereus ATCC 10987, complete genomehypothetical protein5e-0961.6
NC_006274:4408734:4408734440873444104521719Bacillus cereus E33L, complete genomehypothetical protein5e-0961.6
NC_011761:2785660:2789828278982827915581731Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completeDNA polymerase X family protein9e-0960.8
NC_011206:2685499:2689667268966726913971731Acidithiobacillus ferrooxidans ATCC 53993, complete genomePHP domain protein9e-0960.8
NC_017047:1796000:179974817997481800167420Rahnella aquatilis HX2 chromosome, complete genomeputative hydrolase1e-0860.1
NC_014483:195321:204956204956205780825Paenibacillus polymyxa E681 chromosome, complete genomeProbable histidinol-phosphatase (HolPase)7e-0857.8
NC_006347:1815687:183845818384581839291834Bacteroides fragilis YCH46, complete genomeputative histidinol-phosphatase9e-0857.4
NC_009778:2227627:227269522726952273147453Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein1e-0757
NC_014364:394899:464885464885465736852Spirochaeta smaragdinae DSM 11293 chromosome, complete genomehistidinol phosphate phosphatase HisJ family8e-0754.3
NC_006322:2886404:2888778288877828904931716Bacillus licheniformis ATCC 14580, complete genomehypothetical protein1e-0653.5
NC_006270:2886193:2888567288856728902911725Bacillus licheniformis ATCC 14580, complete genomehypothetical protein1e-0653.5
NC_020411:1333352:1349460134946013511901731Hydrogenobaculum sp. HO, complete genomePHP domain protein2e-0653.1
NC_015557:1333158:1349266134926613509961731Hydrogenobaculum sp. 3684 chromosome, complete genomePHP domain protein2e-0653.1
NC_010718:1865992:1886501188650118882161716Natranaerobius thermophilus JW/NM-WN-LF, complete genomePHP domain protein3e-0652.4
NC_011126:1345984:1359234135923413609641731Hydrogenobaculum sp. Y04AAS1, complete genomePHP domain protein5e-0651.6