Pre_GI: BLASTP Hits

Some Help

Query: NC_004557:2289135:2297032 Clostridium tetani E88, complete genome

Start: 2297032, End: 2297850, Length: 819

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009633:286677:300284300284301057774Alkaliphilus metalliredigens QYMF chromosome, complete genomecobalamin adenosyltransferase1e-69263
NC_017179:2067015:208080820808082081569762Clostridium difficile BI1, complete genomeethanolamine/propanediol utilization cobalamin adenosyltransferase2e-60232
NC_013315:2059007:207280020728002073561762Clostridium difficile CD196 chromosome, complete genomeethanolamine/propanediol utilization cobalamin adenosyltransferase2e-60232
NC_003366:1091766:110605011060501106865816Clostridium perfringens str. 13, complete genomeethanolamine utilization cobalamin adenosyltransferase2e-60232
NC_008261:1048515:106282510628251063601777Clostridium perfringens ATCC 13124, complete genomeethanolamine utilization cobalamin adenosyltransferase7e-58224
NC_015275:4493500:449759644975964498363768Clostridium lentocellum DSM 5427 chromosome, complete genomecobalamin adenosyltransferase9e-52203
NC_018870:705900:728437728437729156720Thermacetogenium phaeum DSM 12270 chromosome, complete genomecobalamin adenosyltransferase3e-45182
NC_014614:284005:299060299060299824765Clostridium sticklandii, complete genomeputative cobalamin adenosyltransferase in ethanolamine utilization2e-44179
NC_009253:1381401:139151813915181392288771Desulfotomaculum reducens MI-1 chromosome, complete genomecobalamin adenosyltransferase2e-42172
NC_013517:1055854:112725511272551128001747Sebaldella termitidis ATCC 33386, complete genomecobalamin adenosyltransferase8e-40164
NC_013192:63111:792097920979991783Leptotrichia buccalis DSM 1135, complete genomecobalamin adenosyltransferase3e-38159
NC_017243:1813158:182308818230881823849762Brachyspira intermedia PWS/A chromosome, complete genomeethanolamine utilization cobalamin adenosyltransferase2e-37155
NC_016584:1998000:2029244202924420306681425Desulfosporosinus orientis DSM 765 chromosome, complete genomepropanediol utilization protein9e-37154
NC_016584:1714507:1721473172147317228521380Desulfosporosinus orientis DSM 765 chromosome, complete genomepropanediol utilization protein2e-36153