Pre_GI: BLASTP Hits

Some Help

Query: NC_004088:3923804:3928152 Yersinia pestis KIM, complete genome

Start: 3928152, End: 3928433, Length: 282

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010634:4001154:400695840069584007221264Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein1e-44178
NC_010465:660207:672399672399673013615Yersinia pseudotuberculosis YPIII, complete genomefilamentation induced by cAMP protein Fic1e-37155
NC_008149:587689:603714603714603917204Yersinia pestis Nepal516, complete genomehypothetical protein1e-32137
NC_008150:3495851:350105335010533501256204Yersinia pestis Antiqua, complete genomehypothetical protein1e-32137
NC_009381:460358:476110476110476313204Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-32137
NC_017265:3790750:379351437935143793717204Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein1e-32137
NC_009708:633054:645306645306645863558Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeFic family protein8e-24108
NC_014618:690056:699310699310699864555Enterobacter cloacae SCF1 chromosome, complete genomefilamentation induced by cAMP protein fic7e-1992.4
NC_019902:1:698169817598618Thioalkalivibrio nitratireducens DSM 14787, complete genomeFic family putative cell filamentation protein1e-0961.6
NC_015458:3077804:308985430898543090483630Pusillimonas sp. T7-7 chromosome, complete genomehypothetical protein2e-0961.2