Query: NS_000191:344000 Uncultured Termite group 1 bacterium phylotype Rs-D17, complete
Lineage: uncultured Termite group 1 bacterium; enviromental sample; ; ; Elusimicrobia; Bacteria
General Information: Termite gut symbion. Termites harbor a symbiotic gut microbial community that is responsible for their ability to thrive on recalcitrant plant matter. Found specifically within the cells of the cellulolytic flagellate Trichonympha agilis in the gut of the termite Reticulitermes speratus.
Subject: NC_011896:2240990 Mycobacterium leprae Br4923, complete genome
Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.