Query: NC_020291:3900046 Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome Lineage: Clostridium saccharoperbutylacetonicum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria General Information: This organism produces acetone, butanol and ethanol when grown on molasses, corn mash and other sugar and starch containing substrates.
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General Information: This strain (originally ZK, now E33L; Ethosha National Park, Namibia; isolate number 33; Large colony) was isolated from a swab of a dead zebra carcass in April, 1996. Soil microorganism that can cause food poisoning. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.