Query: NC_020181:527592 Enterobacter aerogenes EA1509E, complete genome Lineage: Enterobacter aerogenes; Enterobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: This organism is part of the normal human gastrointestinal flora which is able to cause opportunistic infections such as bacteremia, endocarditis and infections of the urinary and lower respiratory tract.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.