Query: NC_020133:5485528 Mycobacterium liflandii 128FXT, complete genome Lineage: Mycobacterium liflandii; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria General Information: First isolated from a colony of African clawed frogs. This organism causes a fatal systemic disease in frogs often characterized by skin lesions. Mycobacterium liflandii produces a polyketide toxin mycolactone E and two highly antigenic proteins ESAT-6 and CFP-10 which account, in part, for its pathogenicity.
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General Information: Isolated from a beaver that died of tularemia in Oklahoma in 1978. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.