Query: NC_019962:2189432 Natrinema pellirubrum DSM 15624, complete genome Lineage: Natrinema pellirubrum; Natrinema; Halobacteriaceae; Halobacteriales; Euryarchaeota; Archaea General Information: Country: Italy; Isolation: Red heat in salted hides (spoiled fish); Temp: Mesophile. Natrinema pellirubrum, formerly Halobacterium salinarium is a halophilic archaea requiring at least 1.7 M NaCl for growth and able to grow at salt concentrations of up to 4.3 M.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.