Query: NC_018750:5828000 Streptomyces venezuelae ATCC 10712, complete genome Lineage: Streptomyces venezuelae; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Streptomyces venezuelae strain ATCC 10712, isolated from soil in Caracas, Venezuela in about 1948, grows in a diffuse and homogenous manner in a variety of liquid media, and in some sporulates to near completion. This organism produces a number of secondary metabolites which may be of industrial or pharmaceutical interest. Soil actinomycete.
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General Information: Lawsonia intracellularis PHE/MN1-00 was isolated from intestinal mucosal lesions in pigs that had proliferative enteropathy (PE). When introduced into health pigs, this organism produced the clinical and histological signs of PE. Causative agent for proliferative enteropathy in swine. This organism causes proliferative enteropathy (ileitis) in swine and other domesticated animals resulting in severe losses each year. This obligate intracellular pathogen infects the mucosa of the lower intestinal tract by initially infecting crypt cells, which are precursors that normally grow and divide in order to replace the epithelial cells. Once infection occurs, the crypt cells are stimulated to grow and divide abnormally, resulting in the proliferative phenotype. In severe cases of the disease the entire bowel can become affected and persist for up to 40 days, greatly affecting the host animal.