Query: NC_018750:1591895 Streptomyces venezuelae ATCC 10712, complete genome Lineage: Streptomyces venezuelae; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Streptomyces venezuelae strain ATCC 10712, isolated from soil in Caracas, Venezuela in about 1948, grows in a diffuse and homogenous manner in a variety of liquid media, and in some sporulates to near completion. This organism produces a number of secondary metabolites which may be of industrial or pharmaceutical interest. Soil actinomycete.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.