Query: NC_018704:645843 Amphibacillus xylanus NBRC 15112, complete genome Lineage: Amphibacillus xylanus; Amphibacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Amphibacillus xylanus is an alkaliphilic microorganism that grows at pH 8 - 10. This organism is also able to digest xylan aerobically and anaerobically. Facultative anaerobic, spore-forming, Gram-positive bacterium isolated from alcaline compost of manure with grass and rice straw.
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General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.