Query: NC_018604:2053585 Brachyspira pilosicoli WesB complete genome
Lineage: Brachyspira pilosicoli; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria
General Information: Brachyspira pilosicoli is an anaerobic spirochete that colonizes the large intestine of various species of birds and animals and humans. It attaches to colonic enterocytes in a condition called 'intestinal spirochetosis', characterized by mild colitis, diarrhea and reduced growth.
Subject: NC_012225:1497934 Brachyspira hyodysenteriae WA1, complete genome
Lineage: Brachyspira hyodysenteriae; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria
General Information: Brachyspira hyodysenteriae is the causative agent of swine dysentery, which is a severe mucohemorrhagic diarrheal disease of pigs that has economic significance for pork-producing countries. The bacterium can survive for several weeks in cold moist conditions but not under warm dry conditions. It spreads slowly, building up in numbers as the dose rate of the causal agent builds up in the environment. Pigs that recover develop a low immunity and rarely suffer from the disease again. It can be spread by other organisms (flies, mice, birds and dogs) or external mechanical factors; its main habitat is the porcine cecum and colon. It is chemotactically attracted to mucin which it penetrates with a corkscrew-like motility.