Pre_GI: SWBIT SVG BLASTP

Query: NC_017518:577159 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_010170:2374852 Bordetella petrii, complete genome

Lineage: Bordetella petrii; Bordetella; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Bordetella petrii strain DSM12804 was initially isolated from river sediment. Unlike other members of the genus, this organism is not known to be associated with humans or other warm-blooded animals. Bordetella petrii also differs from other Bordetella species in that it is a facultative anaerobe.