Pre_GI: SWBIT SVG BLASTP

Query: NC_017518:2041282 Neisseria meningitidis NZ-05/33 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_015164:2078500 Bacteroides salanitronis DSM 18170 chromosome, complete genome

Lineage: Bacteroides salanitronis; Bacteroides; Bacteroidaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: Country: Japan; Environment: Host; Isolation: caecum of chicken; Temp: Mesophile; Temp: 37C. This group of microbes constitute the most abundant members of the intestinal microflora of mammals. Typically they are symbionts, but they can become opportunistic pathogens in the peritoneal (intra-abdominal) cavity. This organism produces many extracellular enzymes which assist in the breakdown of complex plant polysaccharides such as cellulose and hemicellulose and host-derived polysaccharides such as mucopolysaccharides. Bacteroides salanitronis is a species of strictly anaerobic, non-spore-forming, non-motile, Gram-negative rods. It was isolated from caecum of a healthy chicken.