Query: NC_017518:150991 Neisseria meningitidis NZ-05/33 chromosome, complete genome Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.
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General Information: This strain is a non-biofilm-forming, non-infection associated strain used for detection of residual antibiotics in food products. Common skin bacterium. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is the most prevalent and persistent Staphylococcus species on human skin. Has emerged as a common cause of nosocomial (hospital-acquired) infections, including catheter-associated infections and septicemia, particularly in immunocompromised patients. Resistant to many antibiotics including penicillins and cephalosporins.