Pre_GI: SWBIT SVG BLASTP

Query: NC_017517:1377617 Neisseria meningitidis M01-240355 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_007644:3229 Moorella thermoacetica ATCC 39073, complete genome

Lineage: Moorella thermoacetica; Moorella; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: Moorella thermoacetica, formerly Clostridium thermoaceticum, can grow on hydrogen and fix carbon dioxide or carbon monoxide with the production of acetate. It is found at the bottom of stagnant ponds and forms extremely heat-resistant spores.