Pre_GI: SWBIT SVG BLASTP

Query: NC_017517:898771 Neisseria meningitidis M01-240355 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_013440:5509790 Haliangium ochraceum DSM 14365, complete genome

Lineage: Haliangium ochraceum; Haliangium; Kofleriaceae; Myxococcales; Proteobacteria; Bacteria

General Information: Isolation: Seaweed collected from coastal sands from Japan; Temp: Mesophile; Temp: 30C; Habitat: Coastal, Marine, Sand. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. Haliangium ochraceum is a true marine organism requiring 1-3% NaCl for growth.