Pre_GI: SWBIT SVG BLASTP

Query: NC_017517:898771 Neisseria meningitidis M01-240355 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_010544:850502 Candidatus Phytoplasma australiense, complete genome

Lineage: Phytoplasma australiense; Phytoplasma; Acholeplasmataceae; Acholeplasmatales; Tenericutes; Bacteria

General Information: Phytoplasmas inhabit phloem (food-conducting vascular tissue) sieve elements of plants where they cause a variety of diseases. Transmission between plants is via insects that feed on the phloem. Candidatus Phytoplasma australiense was identified in diseased Chardonnay grapevines from South Australia. Symptoms include a yellowing of the leaves and reduced leaf size, which leads to reduced plant size and lower yields.