Pre_GI: SWBIT SVG BLASTP

Query: NC_017516:917817 Neisseria meningitidis H44/76 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_010545:11950 Corynebacterium urealyticum DSM 7109, complete genome

Lineage: Corynebacterium urealyticum; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Corynebacterium urealyticum DSM 7109 (ATCC 43042, NCTC 12011) was isolated from a case of cystitis. Corynebacterium urealyticum is a member of normal human skin and mucosal flora. This organism, however, can colonize the urinary tract causing infections.