Pre_GI: SWBIT SVG BLASTP

Query: NC_017515:1653306 Neisseria meningitidis M04-240196 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_012691:2146473 Tolumonas auensis DSM 9187, complete genome

Lineage: Tolumonas auensis; Tolumonas; Aeromonadaceae; Aeromonadales; Proteobacteria; Bacteria

General Information: Isolation: freshwater mud; Temp: Mesophile; Habitat: Fresh water, Mud; Isolation: sediment of freshwater lake; Country:Switzerland. Tolumonas auensis is able to produce the aromatic hydrocarbon tolulene when grown on phenylalanine, phenyllactate,and phenylpyruvate with a separate carbon source. This organism can also produce tyrosines when grown with phenol.