Pre_GI: SWBIT SVG BLASTP

Query: NC_017515:800000 Neisseria meningitidis M04-240196 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_008536:5421036 Solibacter usitatus Ellin6076, complete genome

Lineage: Solibacter usitatus; Solibacter; Solibacteraceae; Solibacterales; Acidobacteria; Bacteria

General Information: This strain was isolated from a rotationally grazed pasture of perennial ryegrass and white clover in Victoria, Australia. Solibacter usitatus is a member of the Acidobacteria, a group of organisms commonly found in water reservoirs, microbial mats, many different soil types, marine and freshwater sediments, as well as in hot-spring mats and sediments, etc. Furthermore, they sometimes form the dominant group in a habitat. These bacteria are involved in the first step of destruction of biologically complex molecules produced by autotrophic (capable of synthesizing their own nutrients) microorganisms.