Pre_GI: SWBIT SVG BLASTP

Query: NC_017514:863485 Neisseria meningitidis M01-240149 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_014012:3812754 Shewanella violacea DSS12, complete genome

Lineage: Shewanella violacea; Shewanella; Shewanellaceae; Alteromonadales; Proteobacteria; Bacteria

General Information: Shewanella violacea DSS12 was isolated from mud, taken at a depth of 5110 m, from the Ryukyu Trench in the Philippine Sea. Shewanella violacea is psychrophilic and barophilic, with an optimum growth temperature and pressure of 8 degrees C and 30 MPa, respectively. This organism is able to grow at pressures from 0.1 MPa to 70Mpa, however, no growth occurs a temperatures above 20 degrees C.