Pre_GI: SWBIT SVG BLASTP

Query: NC_017513:997716 Neisseria meningitidis G2136 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_012796:2683711 Desulfovibrio magneticus RS-1, complete genome

Lineage: Desulfovibrio magneticus; Desulfovibrio; Desulfovibrionaceae; Desulfovibrionales; Proteobacteria; Bacteria

General Information: Isolated from freshwater sulfide-rich mud of a waterway near Kameno river, Wakayama, in Japan. This organism is a sulfate-reducing delta proteobacterium which synthesizes intracellular magnetite particles. Desulfovibrio magneticus produces irregular, membrane-bound magnetite particles, unlike other magnetite-producing bacteria which contain crystalline magnetite in the cytoplasm. Desulfovibrio magneticus does not migrate along a magnetic field but swims randomly.