Pre_GI: SWBIT SVG BLASTP

Query: NC_017512:2161000 Neisseria meningitidis WUE 2594, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_015633:413587 Vibrio anguillarum 775 chromosome chromosome I, complete sequence

Lineage: Vibrio anguillarum; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Listonella anguillarum, formerly Vibrio anguillarum is an opportunistic pathogen in economically important marine fish such as eel, flounder and salmon. This disease causes lesions on the skin and around the mouth and gills of the fish often progressing to a systemic infection causing death. If left untreated this disease can cause significant losses in commercial hatcheries.