Pre_GI: SWBIT SVG BLASTP

Query: NC_017512:2087098 Neisseria meningitidis WUE 2594, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_012587:1203103 Rhizobium sp. NGR234, complete genome

Lineage: Sinorhizobium fredii; Sinorhizobium; Rhizobiaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism, much like other Rhizobia, forms a symbiotic relationship with a leguminous plant, such as soybean, cowpea or pigeon pea. Expression of nodulation genes results in production of a nodulation signal which the plant cell recognizes inducing root nodule formation. The plant cell provides carbon compounds for the bacterium to grow on.