Query: NC_017511:602000 Neisseria gonorrhoeae TCDC-NG08107 chromosome, complete genome Lineage: Neisseria gonorrhoeae; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria General Information: One of two pathogenic Neisseria, this species causes the sexually transmitted disease (STD) gonorrhea, which is the leading reportable STD in adults in the USA. This human-specific organism colonizes and invades the mucosal surface of the urogenital epithelium, crosses the epithelial barrier, and ends up multiplying on the basement membrane. The Opa proteins are responsible for the opaque colony phenotype due to the tight junctions between adjacent Neisseria, and are also responsible for tight adherence to host cells. This organism, like Neisseria meningitidis, is also naturally competent for DNA uptake.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Environment: Rhizosphere, Host, Rhizosphere-colonizing; Temp: Mesophile. This species is an uncommon but serious source of infection in patients with breathing tubes such as endotracheal or tracheostomy tubes, or with chronically indwelling urinary catheters. Although the organism can colonize the devices without causing an infection, under certain conditions it can cause pneumonia, urinary tract infections, or an infection of the blood. This organism can also cause infection in immunocompromised patients. It has resistance to many commonly used antibiotics and therefore is often difficult to eradicate. Most strains are resistant to co-trimoxazole.