Pre_GI: SWBIT SVG BLASTP

Query: NC_017505:926801 Neisseria meningitidis alpha710 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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BLASTP Alignment.txt

Subject: NC_009832:622969 Serratia proteamaculans 568, complete genome

Lineage: Serratia proteamaculans; Serratia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated as a root endophyte from Populus trichocarpa. This species is associated with a serious form of pneumonia in humans, and is the causal agent of amber disease in the grass grub. Interestingly, it also contains an inducible activator which promotes the growth of soybeans under greenhouse conditions.