Pre_GI: SWBIT SVG BLASTP

Query: NC_017505:1338661 Neisseria meningitidis alpha710 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_003295:998000 Ralstonia solanacearum GMI1000, complete genome

Lineage: Ralstonia solanacearum; Ralstonia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain is a race 1 strain isolated from the tomato plant and is also pathogenic on Arabidopsis thaliana. It specifically invades the plant xylem. Plant pathogen. This organism is a phytopathogen that is found in the soil and causes systemic wilting disease in many important food crops such as tomatoes, potatoes, bananas, tobacco, pepper, peanut, ginger, and eucalyptus. It can infect plants found in over 50 different families and this pathogen can be carried asymptomatically in some species.