Pre_GI: SWBIT SVG BLASTP

Query: NC_017430:350668 Chlamydia trachomatis G/11222 chromosome, complete genome

Lineage: Chlamydia trachomatis; Chlamydia; Chlamydiaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. This species causes infection that leads to blindness and sexually transmitted diseases in humans. There are 15 serovariants that preferentially cause disease in either the eye or the urogenital tract. The trachoma (infection of the mucous membrane of the eyelids) biovars are noninvasive and can cause blinding trachoma (variants A, B, Ba, and C), or sexually transmitted diseases (variants, D, E, F, G, H, I, J, and K). The lymphogranuloma venereum biovars (variants L1, L2, and L3) can cross the epithelial cells of mucous membranes and then travel through the lymphatic system where they multiply within mononuclear phagocytes found within the lymph nodes.

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BLASTP Alignment.txt

Subject: NC_004829:312750 Mycoplasma gallisepticum R, complete genome

Lineage: Mycoplasma gallisepticum; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: Causes respiratory disease in birds. This genus currently comprises more than 120 obligate parasitic species found in a wide spectrum of hosts, including humans, animals, insects and plants. The primary habitats of human and animal mycoplasmas are mucous membranes of the respiratory and urogenital tracts, eyes, mammary glands and the joints. Infection that proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invasion, results in prolonged intracellular persistence that may cause lethality. Once detected in association with their eukaryotic host tissue, most mycoplasmas can be cultivated in the absence of a host if their extremely fastidious growth requirements are met.