Query: NC_017268:1 Treponema pallidum subsp. pallidum str. Chicago chromosome,
Lineage: Treponema pallidum; Treponema; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria
General Information: This organisms is divided into subspecies each of which causes a specific disease. pallidum causes the venereal disease syphilis. pertenue, carateum and endemicum cause the skin infections yaws, pinta and bejel, respectively. Cells are motile, slender, helically shaped flexible organisms, 0.1-0.18 microns in diameter and 6-20 microns long.
Subject: NC_010634:1755548 Yersinia pseudotuberculosis PB1/+, complete genome
Lineage: Yersinia pseudotuberculosis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: Environmental bacterium that causes gastrointestinal disease. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. This organism was first isolated in 1883 by Malassez and Vignal and is termed pseudotuberculosis since it causes lesions in the lung that are similar to those observed during tuberculosis infection. It is ubiquitous in the environment and is a food and waterborne pathogen that affects animals as well as humans by causing gastroenteritis like Yersinia enterocolitica.