Query: NC_017248:721764 Brucella melitensis NI chromosome chromosome I, complete sequence Lineage: Brucella melitensis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria General Information: They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Temp: Mesophile; Habitat: Host. Pectobacterium carotovorum causes soft-rot diseases of various plant hosts through degradation of the plant cell walls. Formerly Erwinia, these organisms are plant-specific pathogens that invade the vascular systems of plants. Pectobacterium colonize the intercellular spaces of plant cells and deliver potent effector molecules (Avr - avirulence) through a type III secretion system (Hrp - hypersensitive response and pathogenicity). Avr proteins control host-bacterium interactions, including host range. Expression of the plant cell-wall-degrading enzymes is controlled through a quorum-sensing mechanism that quantifies the number of Pectobacterium bacteria through measurement of the concentration of small molecules (acyl homoserine lactones) produced by Pectobacterium.