Query: NC_017186:7480714 Amycolatopsis mediterranei S699 chromosome, complete genome
Lineage: Amycolatopsis mediterranei; Amycolatopsis; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Amycolatopsis belongs to the actinomycete family Pseudonocardiaceae. Amycolatopsis mediterranei produces the antibiotic rifamycin, derivatives of which are used for curing tuberculosis and leprosy. Antibiotic producing bacterium.
Subject: NC_006348:2738425 Burkholderia mallei ATCC 23344 chromosome 1, complete sequence
Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: This type strain came from a Chinese patient in Burma who had glanders in 1944. Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.