Query: NC_017186:7480714 Amycolatopsis mediterranei S699 chromosome, complete genome
Lineage: Amycolatopsis mediterranei; Amycolatopsis; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Amycolatopsis belongs to the actinomycete family Pseudonocardiaceae. Amycolatopsis mediterranei produces the antibiotic rifamycin, derivatives of which are used for curing tuberculosis and leprosy. Antibiotic producing bacterium.
Subject: NC_000963:803435 Rickettsia prowazekii str. Madrid E, complete genome
Lineage: Rickettsia prowazekii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.