Query: NC_017167:1088713 Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1 Lineage: Alicyclobacillus acidocaldarius; Alicyclobacillus; Alicyclobacillaceae; Bacillales; Firmicutes; Bacteria General Information: Alicyclobacillus acidocaldarius, formerly Bacillus acidocaldarius was first isolated from an acidic creek in Yellowston National Park and grows at a pH of 3.6. This organism is both thermophilic and acidophilic and produces heat and acid stable enzymes, such as amylase and esterase, which may be important in industry.
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General Information: This strain was obtained from an infected tick and maintained by serial infection in mice. Obligate intracellular bacterium and causative agent of heartwater. This organism causes heartwater, a disease with a high mortality rate that affects both wild and domesticated ruminants in sub-Saharan Africa and parts of the Caribbean. The name heartwater refers to the hydropericardium (excessive fluid in the sac surrounding the heart) commonly found associated with infection. This organism is found in membrane-bound vacuoles in endothelial cells and neutrophils and is an obligate intracellular parasite.