Pre_GI: SWBIT SVG BLASTP

Query: NC_017160:3094768 Yersinia pestis D182038 chromosome, complete genome

Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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BLASTP Alignment.txt

Subject: NC_006834:787500 Xanthomonas oryzae pv. oryzae KACC10331, complete genome

Lineage: Xanthomonas oryzae; Xanthomonas; Xanthomonadaceae; Xanthomonadales; Proteobacteria; Bacteria

General Information: This plant pathogen affects rice plants by causing leaf blight, a major problem in Asian countries where rice production occurs on an industrial scale. Causes disease in rice. These organisms are almost exclusively found associated with their plant hosts and are not found free in the soil. Xanthomonas oryzae contains two pathovars which cause enconomically significant diseases in rice. Xanthomonas oryzae pathovar oryzae causes bacterial leaf blight which is one of the most serious diseases of rice. This disease is common in temperate and tropical areas and can cause significant crop loss.