Pre_GI: SWBIT SVG BLASTP

Query: NC_017095:2143845 Fervidobacterium pennivorans DSM 9078 chromosome, complete genome

Lineage: Fervidobacterium pennivorans; Fervidobacterium; Thermotogaceae; Thermotogales; Thermotogae; Bacteria

General Information: Country: Italy; Environment: Hot spring, Mud, Sediment; Isolation: hot mud of spa; Temp: Thermophile; Temp: 65C. This organism is an extreme thermophilic member of the Thermotogales and has the characteristic morphology of one or more cells contained in a sheath-like envelope which extends beyond the cell wall. This organism produces a protease which is able to degrade keratin.

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Subject: NC_007799:968499 Ehrlichia chaffeensis str. Arkansas, complete genome

Lineage: Ehrlichia chaffeensis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.