Query: NC_017068:2661419 Selenomonas ruminantium subsp. lactilytica TAM6421, complete Lineage: Selenomonas ruminantium; Selenomonas; Veillonellaceae; Selenomonadales; Firmicutes; Bacteria General Information: This organism is a member of the normal flora of the sheep rumen. The genus Selenomonas constitutes a group of motile crescent-shaped bacteria and includes species living in the gastrointestinal tracts of animals, in particular, the Ruminants. Despite being Firmicutes they stain Gram-negative and possess a double bilayer. Cells are crescent or bean-shaped with coiled flagella located on the concave surface with an infolding of the cell membrane behind the flagellar attachment point.
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General Information: Citrobacter rodentium is the causative agent of transmissible murine colonic hyperplasia in mice. This disease is characterized by a hyperproliferation of the epithelial cells in the colon similar to that found in humans suffering from idiopathic inflammatory bowel disease. In addition this organism contains virulence factors similar to those found in enterohemorrhagic Escherichia coli and enteropathogenic E. coli. C. rodentium are being used as models for studying mucosal response to infection, colon tumor production, and virulence associated with pathogenic E. coli.