Query: NC_017065:274165 Rickettsia slovaca str. D-CWPP chromosome, complete genome Lineage: Rickettsia slovaca; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain was recovered from an acutely infected cow from Northern Idaho, USA and bears an msp1a genotype of JBB. This strain is transmitted by ticks and is known to be virulent. This organism is the causative agent of bovine anaplasmosis and is an obligate intracellular pathogen. Transmission occurs via an arthropod vector (tick) and is a major problem in tropical regions where it causes severe morbidity in cattle populations. The bacterium lives intracellularly within membrane-bound vesicles in the host erythrocyte, a cell type which it specifically targets, resulting in severe anemia for the host organism.