Query: NC_017065:930985 Rickettsia slovaca str. D-CWPP chromosome, complete genome Lineage: Rickettsia slovaca; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms.
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General Information: Treponema denticola ATCC 35405 was isolated from a human periodontal pocket. Associated with periodontal disease. This organism is a member of the spirochaetales and is a motile, slender, helically shaped flexible organism. Obligately anaerobic growth occurs at 30-42°C, with a pH of 6.5-8.0. The bacterium is commonly found in the oral cavity of humans and often associated with periodontal disease, an inflammation of the gum tissue that frequently precedes bone resorbtion and subsequent tooth loss.