Pre_GI: SWBIT SVG BLASTP

Query: NC_017062:61500 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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BLASTP Alignment.txt

Subject: NC_013061:987744 Pedobacter heparinus DSM 2366, complete genome

Lineage: Pedobacter heparinus; Pedobacter; Sphingobacteriaceae; Sphingobacteriales; Bacteroidetes; Bacteria

General Information: Isolation: Soil; Temp: Mesophile; Temp: 25 - 30C; Habitat: Soil. Formerly Sphingobacterium heparinum this organism was isolated from soil. This organism is able to degrade heparin and heparan sulfate glycosaminoglycans, which are components of extracellular polysaccharides and the cell surface.