Pre_GI: SWBIT SVG BLASTP

Query: NC_017062:33268 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

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BLASTP Alignment.txt

Subject: NC_008390:2643653 Burkholderia cepacia AMMD chromosome 1, complete sequence

Lineage: Burkholderia ambifaria; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Isolated from the rhizosphere of healthy pea plants in Wisconsin, USA, in 1985. Pathogenic in cystic fibrosis patients. These bacteria present great versatility to adapt to diverse environments, and are capable of degrading pollutants in water and soil, and fixing atmospheric nitrogen. This species include strains isolated from cystic fibrosis patients as well as strains with potential use in biocontrol.