Query: NC_017056:995500 Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genome Lineage: Rickettsia prowazekii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This organism was first described in 1953 in Japan as causing Sennetsu fever. Causes an infectious mononucleosis-like disease. Like other Ehrlichia, this organism is an obligate intracellular pathogen. It can be transmitted from fish flukes (trematodes) to humans, and was one of the first Ehrlichia that was found to cause a human-specific illness.