Pre_GI: SWBIT SVG BLASTP

Query: NC_017044:278500 Rickettsia parkeri str. Portsmouth chromosome, complete genome

Lineage: Rickettsia parkeri; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Animal pathogen in Mammalia (intracellular obligate). Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Rickettsia parkeri, a member of the spotted fever group Rickettsia (SFGR), was first isolated from the Gulf Coast tick, Amblyomma maculatum, in 1937. In 2004, the first confirmed human infection with R. parkeri was reported in a 40-year-old man from the Tidewater area of coastal Virginia. The agent was isolated in cell culture from an eschar biopsy specimen and designated the Portsmouth strain; recently, the first recognized case of tick bite-associated human infection was described.

Subject: NC_012779:610509 Edwardsiella ictaluri 93-146, complete genome

Lineage: Edwardsiella ictaluri; Edwardsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Edwardsiella ictaluri is the causative agent of enteric septicemia in catfish (ESC), an economically significant disease of farm-raised catfish. The acute form of ESC causes bacterial septicemia (proliferation of bacteria in the blood) which rapidly leads to death. The chronic form of this disease causes a characteristic head lesion, and may also proceed to septicemia and death. Two plasmids, which are consistently present in Edwardsiella ictaluri isolates, have been sequenced. Both plasmids contain genes for the type III secretory system, which is involved in translocating pathogenicity proteins into the eukaryotic cell.