Query: NC_017042:310000 Rickettsia rhipicephali str. 3-7-female6-CWPP chromosome, complete Lineage: Rickettsia rhipicephali; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: Animal pathogen in Mammalia (intracellular obligate). Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Rickettsia rhipicephali was first identified in Rhipicephalus sanguineus ticks.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.