Query: NC_017028:180219 Candidatus Rickettsia amblyommii str. GAT-30V chromosome, complete Lineage: Rickettsia amblyommii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: Animal pathogen in Mammalia (intracellular obligate). Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Rickettsia amblyommii, a member of the spotted fever antigenic and genetic group Rickerriae infects Amblyomma ticks in the United States, Panama, French Guiana, Brazil, and Argentina.
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General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.