Query: NC_017028:1131896 Candidatus Rickettsia amblyommii str. GAT-30V chromosome, complete
Lineage: Rickettsia amblyommii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Animal pathogen in Mammalia (intracellular obligate). Rickettsiae are obligate intracellular Gram-negative bacteria mostly found in arthropods, some of which cause mild to severe diseases in humans. Rickettsia amblyommii, a member of the spotted fever antigenic and genetic group Rickerriae infects Amblyomma ticks in the United States, Panama, French Guiana, Brazil, and Argentina.
Subject: NC_008245:141982 Francisella tularensis subsp. tularensis FSC 198, complete genome
Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria
General Information: This subspecies is virulent in humans, the strain FSC 198 was isolated in Slovakia from a mite and is virulent in an animal model. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.