Pre_GI: SWBIT SVG BLASTP

Query: NC_016948:2033311 Mycobacterium intracellulare MOTT-64 chromosome, complete genome

Lineage: Mycobacterium intracellulare; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium intracellulare is a member of the Mycobacterium avium complex (MAC). These organisms cause tuberculosis in birds, and pulmonary and disseminated infections in immunocompromized humans. Mycobacterium intracellulare is also an important contributor to MAC-associated pulmonary infections in immunocompetent patients. Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Mycobacterium intracellulare can also be isolated from the environment and, like other environmental organisms, is able to form and survive in biofilms.

Subject: NC_015713:1594114 Simkania negevensis Z chromosome gsn.131, complete genome

Lineage: Simkania negevensis; Simkania; Simkaniaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: This bacterium is named after Simona Kahane who discovered the organism as a contaminant in cell cultures at Ber Sheva, in the Negev Desert, Israel, in 1993. Simkania negevensis is a member of the order Chlamydiales and can reside intracellularly and has a slow prolonged developmental cycle. It has a wide geographical and environmental distribution and is associated with pneumonia, bronchiolitis and chronic obstructive pulmonary disease, furthermore, it is completely resistant to penicillin and to bacitracin. The natural hosts of Simkania negevensis bacteria might be amoebae.