Pre_GI: SWBIT SVG BLASTP

Query: NC_016947:1455744 Mycobacterium intracellulare MOTT-02 chromosome, complete genome

Lineage: Mycobacterium intracellulare; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium intracellulare is a member of the Mycobacterium avium complex (MAC). These organisms cause tuberculosis in birds, and pulmonary and disseminated infections in immunocompromized humans. Mycobacterium intracellulare is also an important contributor to MAC-associated pulmonary infections in immunocompetent patients. Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Mycobacterium intracellulare can also be isolated from the environment and, like other environmental organisms, is able to form and survive in biofilms.

Subject: NC_015312:5579078 Pseudonocardia dioxanivorans CB1190 chromosome, complete genome

Lineage: Pseudonocardia dioxanivorans; Pseudonocardia; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Country: USA; Environment: Sludge, Fresh water; Isolation: Industrial sludge contaminated; Temp: Mesophile; Temp: 30C. Pseudonocardia members are abundant in diverse environments, and are known to degrade a variety of pollutants. These bacteria are also important in biocatalysis applications and in the production of antibiotics. Pseudonocardia dioxanivorans was first isolated from 1,4-dioxane containing sludge. This organism is able to grow using 1,4-dioxane, a toxic compound used as an industrial solvent, as the sole carbon source.