Pre_GI: SWBIT SVG BLASTP

Query: NC_016944:1594608 Vibrio cholerae IEC224 chromosome I, complete sequence

Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: It was isolated in November of 1994 at the city of Belém/Pa from a stool sample. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

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BLASTP Alignment.txt

Subject: NC_013508:1351447 Edwardsiella tarda EIB202, complete genome

Lineage: Edwardsiella tarda; Edwardsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Edwardsiella tarda is a Gram-negative member of the normal gut microflora of fish, humans, chickens and other animals. This organism is also a serious pathogen of marine and freshwater fish and has been isolated from channel catfish, Japanese eels, flounder, tilapia, and other economically important fish. Infection by this organism is characterized by septicemia, internal abscesses, and skin lesions. This disease is often associated with poor water quality and mortality in aquaculture can be high. Edwardsiella tarda also causes opportunistic infections in humans, most commonly gastroenteritis and wound infections. However, this organism has been isolated from cases of septicemia and meningitis, primarily in immunocompromised patients.