Query: NC_016938:336000 Melissococcus plutonius DAT561 chromosome 1, complete genome Lineage: Melissococcus plutonius; Melissococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: Causative agent of European foulbrood. Insect pathogen. Anaerobic or microaerophilic Gram-positive bacterium. European foulbrood is a disease of honeybee larvae, caused by the bacterium Melissococcus plutonius. It is found on all continents where bees are raised and an economically important disease in many honey-producing countries. Infected larvae usually die rapidly when they are 3-5 days old and in severe cases entire colonies can be lost.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen causes a range of infections similar to those observed with Enterococcus faecalis, including urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart). Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains and has led to the rise of vancomycin-resistant Staphylococcus aureus strains due to the horizontal transfer of Enterococcus antibiotic resistance genes. Little is known about the virulence mechanisms in this organism, but the genome does encode an esp gene for the surface adhesin. Vancomycin resistant isolates are more typically Enterococcus faecium than Enterococcus faecalis.